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TriStar Centennial Medical Center

Symptoms of Rheumatoid Arthritis

Rheumatoid arthritis (RA) most often affects multiple joints throughout the body and the same joints on both sides of the body (example: right hand and left hand are both affected). The symptoms of RA vary from mild to severe depending on the person. Though RA is a chronic condition, symptoms usually flare up and subside intermittently. Some people have symptoms that get worse over time, while others have long periods without symptom flares.

Hallmark symptoms of RA include:

  • Increased pain and stiffness in the morning and after inactivity—common in multiple joints
  • Morning stiffness and pain that usually lasts 30-60 minutes
  • Red, swollen, warm joints
  • Deformed, misshapen joints
Inflamed Joint
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Because inflammation of RA can affect many areas of the body it may also cause:

  • Intense fatigue, decreased energy
  • Muscle aches
  • Decreased appetite
  • Weight loss
  • Fever and sweats
  • Depression
  • Problems sleeping
  • Bumps occurring under the skin—rheumatoid nodules

RA Complications

RA can affect other parts of the body, causing serious health complications. This is especially true if RA remains untreated. Complications of RA include:

  • Dislocation of the cervical spine—Joint damage can weaken the small bones and supporting tissues in the neck.
  • Connective tissue disorders—Inflammation can compress nerves in the joints, which may affect sensation and mobility.
  • Respiratory conditions—Inflammatory responses damage and scar lung tissue making breathing difficult.
  • Cardiovascular problems—Inflammation in blood vessel walls narrows the arteries. Narrowed arteries reduce blood flow to the heart and brain, making the heart pump harder, which can lead to heart failure . Blood clots can get trapped in narrowed arteries, which can lead to a heart attack or stroke
  • Inflammation of the artery walls— arteritis

Revision Information

  • Handout on health: Rheumatoid arthritis. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: Updated August 2014. Accessed October 30, 2014.

  • Rheumatoid arthritis. Arthritis Foundation website. Available at: Accessed October 30, 2014.

  • Rheumatoid arthritis. The Merck Manual Professional Edition website. Available at: Updated May 2013. Accessed October 30, 2014.

  • Rheumatoid arthritis (RA). EBSCO DynaMed website. Available at: Updated April 10, 2014. Accessed October 30, 2014.

  • Wasserman AM. Diagnosis and management of rheumatoid arthritis. Am Fam Physician. 2011;84(11):1245-1252.

The health information in this Health Library is provided by a third party. TriStar Health does not in any way create the content of this information. It is provided solely for informational purposes. It does not constitute medical advice and is not intended to be a substitute for proper medical care provided by a physician. Always consult with your doctor for appropriate examinations, treatment, testing, and care recommendations. Do not rely on information on this site as a tool for self-diagnosis. If you have a medical emergency, call 911.