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TriStar Centennial Medical Center


Trade Names :

  • Apresoline

Hydralazine causes dilation of the walls of blood vessels and is sometimes used to treat hypertension.


Vitamin B6

Hydralazine is known to deplete the blood of vitamin B 6 . Taking B 6 supplements may prevent or reverse side effects of the medication. 1,2

Coenzyme Q10 (CoQ10)

There is some evidence that hydralazine might impair the body's ability to manufacture the substance coenzyme Q 10 (CoQ 10 ). 3 This suggests (but definitely does not prove) that taking CoQ 10 supplements may produce a beneficial effect.

Coleus forskohlii

The herb Coleus forskohlii relaxes blood vessels and might have unpredictable effects if combined with hydralazine.

Revision Information

  • 1

    Shils M, et al. (eds.). Modern nutrition in health and disease, 9th ed. Baltimore: Williams and Wilkins, 1999: 1634.

  • 2

    Goodman L and Gilman A. The pharmacological basis of therapeutics, 9th ed. Hardman J, et al (eds.). New York: McGraw-Hill, 1996: 1562.

  • 3

    Kishi H, et al. Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q 10 -enzymes by clinically used anti-hypertensive drugs. Res Commun ChemPathol Pharmacol 12(3): 533–40, 1975.

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