Hydralazine
Hydralazine
Hydralazine causes dilation of the walls of blood vessels and is sometimes used to treat hypertension.
Vitamin B6
Hydralazine is known to deplete the blood of vitamin B
6
. Taking B
6
supplements may prevent or reverse side effects of the medication.
1,2
Coenzyme Q10 (CoQ10)
There is some evidence that hydralazine might impair the body's ability to manufacture the substance coenzyme Q
10
(CoQ
10
).
3
This suggests (but definitely does not prove) that taking CoQ
10
supplements may produce a beneficial effect.
Coleus forskohlii
The herb
Coleus forskohlii
relaxes blood vessels and might have unpredictable effects if combined with hydralazine.
References
1 Shils M, et al. (eds.). Modern nutrition in health and disease, 9th ed. Baltimore: Williams and Wilkins, 1999: 1634.
2 Goodman L and Gilman A. The pharmacological basis of therapeutics, 9th ed. Hardman J, et al (eds.). New York: McGraw-Hill, 1996: 1562.
3 Kishi H, et al. Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q 10 -enzymes by clinically used anti-hypertensive drugs. Res Commun ChemPathol Pharmacol 12(3): 533–40, 1975.
Revision Information
- Reviewer: EBSCO CAM Review Board
- Review Date: 07/2012 -
- Update Date: 07/25/2012 -
